Original report in

• Randomized, double-blind, placebo-controlled trial of intravenous salbutamol and nebulized ipratropium bromide in early management of severe acute asthma in children presenting to an emergency department.

  Browne GJ, Trieu L, Van Asperen P. Browne GJ, et al. Crit Care Med. 2002 Feb;30(2):448-53. doi: 10.1097/00003246-200202000-00030. Crit Care Med. 2002. PMID: 11889328 Clinical Trial.