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Review
. 2002 Jul 18;35(2):215-7.
doi: 10.1016/s0896-6273(02)00779-1.

The telencephalon saved by TLC

Elizabeth Grove  1
Affiliations
Free article
Review

The telencephalon saved by TLC

Elizabeth Grove. Neuron. .
Free article

Abstract

The telencephalon is one of the most complex parts of the brain, and its patterning is still poorly understood. In this issue of Neuron, describe a novel Wnt antagonist Tlc, a member of the secreted Frizzled-related protein (sFrp) family. Secreted from the anterior boundary of the zebrafish neural plate, Tlc appears to protect the telencephalon from obliteration by a more caudal neural Wnt signal.

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