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Case Reports
. 2002 Jul;50(7):311-4.
doi: 10.1007/BF03032303.

Intrathoracic extramedullary hematopoiesis arising in marble bone disease. Clarifying the genetic disease mechanism

Norihisa Shigemura  1 , Akinori Akashi, Tomoyuki Nakagiri
Affiliations
Case Reports

Intrathoracic extramedullary hematopoiesis arising in marble bone disease. Clarifying the genetic disease mechanism

Norihisa Shigemura et al. Jpn J Thorac Cardiovasc Surg. 2002 Jul.

Abstract

We report a man with intrathoracic extramedullary hematopoiesis accompanied by marble bone disease who underwent thoracoscopic resection safely and definitively, followed by a radionuclide scan. Although intrathoracic extramedullary hematopoiesis is almost always accompanied by hemolytic anemia, this man's hematological data normalized. A consensus on the tumor genesis mechanism has yet to be reached, but the existence of marble bone disease in our case throws new light on the genetic mechanism in intrathoracic extramedullary hematopoiesis.

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