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Case Reports
. 2002 May;24(3):373-7.
doi: 10.1081/jdi-120005372.

Mitomycin-C induced hemolytic uremic syndrome: a case report

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Free article
Case Reports

Mitomycin-C induced hemolytic uremic syndrome: a case report

Rajaram K Gundappa et al. Ren Fail. 2002 May.
Free article

Abstract

Mitomycin-C is used widely in the treatment of malignancies and is associated with serious dose related adverse effects including the occurrence of hemolytic uremic syndrome. We report a patient with a colonic adenocarcinoma who developed hemolytic uremic syndrome after receiving 85 mg/m2 of the drug. The patient was left untreated and died 5 months after this diagnosis was made, of a second malignancy. Differential diagnosis and treatment of this condition are discussed.

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