Dorsoventral patterning: a direct route from ovary to embryo

Abstract

Recent data indicate that Gurken-mediated activation of the EGF receptor in the somatic follicle cells of the Drosophila ovary - required for dorsoventral patterning of the fly embryo - leads to cell-autonomous repression of pipe expression, suggesting that the EGF receptor signaling pathway acts directly to control pipe transcription.