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Review
. 2002 Jul;13(7):1007-15.
doi: 10.1093/annonc/mdf179.

Nasopharyngeal carcinoma

A T C Chan  1 , P M L Teo, P J Johnson
Affiliations
Free article
Review

Nasopharyngeal carcinoma

A T C Chan et al. Ann Oncol. 2002 Jul.
Free article

Abstract

Nasopharyngeal carcinoma (NPC) is endemic in southern China where genetic abnormalities and Epstein-Barr virus (EBV) infection are critical in the pathogenesis of the disease. Circulating EBV-DNA has been shown to improve prognostication and monitoring of NPC patients. Radiotherapy is the mainstay treatment for early disease and concurrent cisplatin/radiotherapy has been demonstrated to prolong survival in locoregionally advanced disease. Ongoing studies of targeting agents and immunotherapeutic approaches may further improve treatment results.

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