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. 2002 Sep;61(9):767-73.
doi: 10.1136/ard.61.9.767.

Key questions concerning paracetamol and NSAIDs for osteoarthritis

P Courtney  1 , M Doherty
Affiliations

Key questions concerning paracetamol and NSAIDs for osteoarthritis

P Courtney et al. Ann Rheum Dis. 2002 Sep.
No abstract available

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Figures

Figure 1
Figure 1
Histogram showing patient preference for NSAIDs or paracetamol for OA (adapted from Pincus et al8 and Wolfe et al15). Both studies show that over 40% of patients either prefer paracetamol or did not express a preference.
Figure 2
Figure 2
Histogram showing the duration of 29 randomised controlled trials of oral NSAIDs for OA (reproduced with permission from www.eBandolier).
Figure 3
Figure 3
Graph showing discontinuation rates of four oral NSAIDs over a 12 month period (reproduced with permission from Scholes et al24). ASA-EC, enteric coated aspirin.
Figure 4
Figure 4
L'Abbé plot showing percentage of patients that achieved at least 50% pain relief from topical NSAIDs or placebo in 12 OA trials (reproduced with permission from www.eBandolier). It is evident that all trials favour the active treatment.
Figure 5
Figure 5
Gastrointestinal mortality associated with NSAIDs37 compared with other causes of death in the United Kingdom (Office for National Statistics 1997).
See this image and copyright information in PMC

Comment in

References

    1. Epidemiology. 2001 Sep;12(5):570-6 - PubMed
    1. Adv Ther. 1994 Jul-Aug;11(4):198-207 - PubMed
    1. J Rheumatol. 1995 Apr;22(4):708-12 - PubMed
    1. Ann Intern Med. 1995 Aug 15;123(4):241-9 - PubMed
    1. BMJ. 1995 Jul 1;311(6996):22-6 - PubMed

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