Effects of ketamine on central sympathetic discharge and the baroreceptor reflex during mechanical ventilation
- PMID: 1218141
- DOI: 10.1093/bja/47.11.1141
Effects of ketamine on central sympathetic discharge and the baroreceptor reflex during mechanical ventilation
Abstract
In rabbits which were ventilated mechanically, with a background anaesthetic of pentobarbitone or after decerebration, ketamine depressed preganglionic sympathetic activity and arterial pressure. Conduction through central baroreceptor pathways, tested by depressor nerve stimulation, showed a selective inhibition of the heart rate response.
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