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Comparative Study
. 2002 Sep;46(9):3094-5.
doi: 10.1128/AAC.46.9.3094-3095.2002.

Comparative activities of the oxazolidinone AZD2563 and linezolid against selected recent North American isolates of Streptococcus pneumoniae

Sue E Baum  1 , Sharon A Crawford, M L McElmeel, Cynthia G Whitney, James H Jorgensen
Affiliations
Comparative Study

Comparative activities of the oxazolidinone AZD2563 and linezolid against selected recent North American isolates of Streptococcus pneumoniae

Sue E Baum et al. Antimicrob Agents Chemother. 2002 Sep.

Abstract

The activity of AZD2563 against 250 highly resistant pneumococci and 267 drug-susceptible isolates was determined. The AZD2563 MICs for 50 and 90% of the strains tested were 1 and 2 micro g/ml and 0.5 and 1 micro g/ml, respectively, for the two isolate groups. These MICs were within 1 log(2) dilution of those of linezolid.

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Figures

FIG. 1.
FIG. 1.
MICs (micrograms per milliliter) of AZD2563 (AZD) and linezolid (LZD) for 250 drug-resistant S. pneumoniae isolates (A) and 267 drug-susceptible S. pneumoniae isolates (B).
See this image and copyright information in PMC

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