doi: 10.1179/135100002125000370.
Antioxidant properties of a Tinospora cordifolia polysaccharide against iron-mediated lipid damage and gamma-ray induced protein damage
Affiliations
- PMID: 12189043
- DOI: 10.1179/135100002125000370
Item in Clipboard
Antioxidant properties of a Tinospora cordifolia polysaccharide against iron-mediated lipid damage and gamma-ray induced protein damage
Redox Rep.
2002.
Free article
Abstract
The antioxidant activity of an arabinogalactan polysaccharide (TSP) isolated from Tinospora cordifolia, an Indian medicinal plant, was studied. The polysaccharide showed good protection against iron-mediated lipid peroxidation of rat brain homogenate as revealed by the thiobarbituric acid reactive substances (TBARS) and lipid hydroperoxide (LOOH) assays. TSP also provided significant protection to protein against gamma-ray induced damage. The protective action can possibly be explained by its very high reactivity towards DPPH, superoxide radicals and the most damaging of radicals, the hydroxyl radical.
Similar articles
-
Free radical scavenging and metal chelation by Tinospora cordifolia, a possible role in radioprotection.Indian J Exp Biol. 2002 Jun;40(6):727-34. Indian J Exp Biol. 2002. PMID: 12587720
-
Antioxidant and radioprotective properties of an Ocimum sanctum polysaccharide.Redox Rep. 2005;10(5):257-64. doi: 10.1179/135100005X70206. Redox Rep. 2005. PMID: 16354414
-
Radioprotective property of polysaccharide in Tinospora cordifolia.Indian J Biochem Biophys. 2003 Feb;40(1):22-6. Indian J Biochem Biophys. 2003. PMID: 22900287
-
Chemistry and Pharmacology of Tinospora cordifolia.Nat Prod Commun. 2017 Feb;12(2):299-308. Nat Prod Commun. 2017. PMID: 30428235 Review.
-
Tinospora cordifolia (Willd.) Hook.f. & Thomson polysaccharides: A review on extraction, characterization, and bioactivities.Int J Biol Macromol. 2023 Feb 28;229:463-475. doi: 10.1016/j.ijbiomac.2022.12.181. Epub 2022 Dec 20. Int J Biol Macromol. 2023. PMID: 36563821 Review.
Cited by
-
Using Guduchi (Tinospora cordifolia) as an eco-friendly feed supplement in human and poultry nutrition.Poult Sci. 2020 Feb;99(2):801-811. doi: 10.1016/j.psj.2019.10.051. Epub 2019 Nov 29. Poult Sci. 2020. PMID: 32029162 Free PMC article. Review.
-
Hypoglycemic and anti-hyperglycemic activity of Guduchi Satva in experimental animals.Ayu. 2013 Oct;34(4):417-20. doi: 10.4103/0974-8520.127726. Ayu. 2013. PMID: 24695802 Free PMC article.
-
Protective Role of Tinospora cordifolia against Lead-induced Hepatotoxicity.Toxicol Int. 2010 Jan;17(1):12-7. doi: 10.4103/0971-6580.68343. Toxicol Int. 2010. PMID: 21042467 Free PMC article.
-
Radiological studies reveal radial differences in the architecture of the polysaccharide capsule of Cryptococcus neoformans.Eukaryot Cell. 2005 Feb;4(2):465-75. doi: 10.1128/EC.4.2.465-475.2005. Eukaryot Cell. 2005. PMID: 15701808 Free PMC article.
-
Changes in MIDAS, Perceived Stress, Frontalis Muscle Activity and Non-Steroidal Anti-Inflammatory Drugs Usage in Patients with Migraine Headache without Aura following Ayurveda and Yoga Compared to Controls: An Open Labeled Non-Randomized Study.Ann Neurosci. 2018 Dec;25(4):250-260. doi: 10.1159/000492269. Epub 2018 Sep 11. Ann Neurosci. 2018. PMID: 31000965 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Miscellaneous
