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Comment
. 2002 Aug;10(2):224-5.
doi: 10.1016/s1097-2765(02)00609-3.

Huntingtin fragments that aggregate go their separate ways

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Huntingtin fragments that aggregate go their separate ways

Marian DiFiglia. Mol Cell. 2002 Aug.
Free article

Abstract

N-terminal region of mutant huntingtin forms intranuclear and cytoplasmic aggregates in neurons that may contribute to neuronal death in Huntington's disease. show that different endoprotease-cleaved huntingtin fragments form nuclear and cytoplasmic inclusions.

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