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Comment
. 2002 Sep 3;99(18):11555-7.
doi: 10.1073/pnas.202448899. Epub 2002 Aug 21.

Host genetic variability and West Nile virus susceptibility

Charles E Samuel  1
Affiliations
Comment

Host genetic variability and West Nile virus susceptibility

Charles E Samuel. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

Figure 1
Figure 1
Biochemical functions of IFN-inducible proteins, including the family of 2′-5′-oligoadenylate synthetases and RNase L nuclease that mediates RNA degradation and apoptosis, the family of Mx protein GTPases that seem to target viral nucleocapsids and inhibit RNA synthesis, the PKR kinase that inhibits translation initiation through phosphorylation of protein synthesis initiation factor eIF-2α, and the ADAR1 adenosine deaminase that edits RNA.
Figure 2
Figure 2
Schematic diagram of flavivirus multiplication cycle.
See this image and copyright information in PMC

Comment on

References

    1. Knipe D M, Howley P M, Griffin D E, Martin M, Roizman B, Straus S E. Fields Virology. 4th Ed. Philadelpha: Lippincott; 2001.
    1. Samuel C E. Clin Microbiol Rev. 2001;14:778–809. - PMC - PubMed
    1. Rebouillat D, Hovanessian A G. J Interferon Cytokine Res. 1999;19:295–308. - PubMed
    1. Kerr I M, Brown R E. Proc Natl Acad Sci USA. 1978;75:256–260. - PMC - PubMed
    1. Zhou A, Paranjape J, Brown T L, Nie H, Naik S, Dong B, Chang A, Trapp B, Fairchild R, Colmenares C, Silverman R H. EMBO J. 1997;16:6355–6363. - PMC - PubMed

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