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Review
. 2002 Aug;30(4):674-80.
doi: 10.1042/bst0300674.

Metal insertion into NiFe-hydrogenases

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Review

Metal insertion into NiFe-hydrogenases

M Blokesch et al. Biochem Soc Trans. 2002 Aug.

Abstract

The synthesis and the insertion of the metallocentre of NiFe-hydrogenases is a complex process, in which seven maturation enzymes plus ATP, GTP and carbamoyl phosphate are involved. The review summarizes what is known about the properties and activities of these auxiliary proteins, and postulates a pathway along which maturation may take place.

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