Drift in the nucleoprotein gene of swine influenza virus (H1N1) causing respiratory disease in pigs
- PMID: 12206303
- DOI: 10.1023/a:1020134511510
Drift in the nucleoprotein gene of swine influenza virus (H1N1) causing respiratory disease in pigs
Abstract
The nucleoprotein (NP) gene of swine influenza H1N1 variant, A/Sw/Quebec/5393/91 (SwQc91) was sequenced. When compared with other H1N1 strains, 12 amino acid (aa) replacements were observed in the 101-484 aa region of the NP protein including two aas, 345 and 430, representing the unique lineage of swine viruses. Phylogenetic analysis showed a drift in the NP gene.
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