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Review
. 2002 Sep;1(9):683-95.
doi: 10.1038/nrd891.

Clinical proteomics: translating benchside promise into bedside reality

Emanuel F Petricoin  1 , Kathryn C Zoon, Elise C Kohn, J Carl Barrett, Lance A Liotta
Affiliations
Review

Clinical proteomics: translating benchside promise into bedside reality

Emanuel F Petricoin et al. Nat Rev Drug Discov. 2002 Sep.

Abstract

The ultimate goal of proteomics is to characterize the information flow through protein networks. This information can be a cause, or a consequence, of disease processes. Clinical proteomics is an exciting new subdiscipline of proteomics that involves the application of proteomic technologies at the bedside, and cancer, in particular, is a model disease for studying such applications. Here, we describe proteomic technologies that are being developed to detect cancer earlier, to discover the next generation of targets and imaging biomarkers, and finally to tailor the therapy to the patient.

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