doi: 10.1067/mpd.2002.127506.
HLA in Egyptian children with biliary atresia
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- PMID: 12219069
- DOI: 10.1067/mpd.2002.127506
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HLA in Egyptian children with biliary atresia
J Pediatr.
2002 Sep.
Abstract
We studied the human leukocytes antigens in 18 Egyptian children with biliary atresia (BA) without extrahepatic congenital malformations. There was a significant increased frequency of both B8 and DR3 (83.3% and 94.4% in patients with BA compared with 6.5% and 14.9% in the general population, respectively). Ten patients had the B8/DR3 haplotype. Our results support the hypothesis that genetic factors may play a role in susceptibility to BA.
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