Clinical Trial
doi: 10.1016/s0163-8343(02)00194-9.
Effect of psychiatric group intervention on natural-killer cell activity and pregnancy rate
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- PMID: 12220802
- DOI: 10.1016/s0163-8343(02)00194-9
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Clinical Trial
Effect of psychiatric group intervention on natural-killer cell activity and pregnancy rate
Gen Hosp Psychiatry.
2002 Sep-Oct.
Abstract
We investigated the effects of psychiatric group intervention on the emotions, natural-killer (NK) cell activity and pregnancy rate in Japanese infertile women by a randomized study. Thirty-seven women completed a 5-session intervention program and were compared with 37 controls. Psychological discomfort and NK-cell activity (47.7% to 34.1%, P<.0001) significantly decreased after the intervention, whereas no significant changes were observed in controls. According to a 1-year follow-up of both groups, the pregnancy rate in the intervention group was significantly higher than that of controls (37.8% vs. 13.5%, P=.03). Psychological group intervention was therefore effective in Japanese infertile women.
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