Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 2002 Sep 10;59(5):744-6.
doi: 10.1212/wnl.59.5.744.

Interferon beta1a and depression in secondary progressive MS: data from the SPECTRIMS Trial

Scott B Patten  1 , Luanne M Metz; SPECTRIMS Study Group
Affiliations
Clinical Trial

Interferon beta1a and depression in secondary progressive MS: data from the SPECTRIMS Trial

Scott B Patten et al. Neurology. .

Abstract

Depression is a suspected side effect of treatment with interferon beta1a in MS. However, an association with depression has not been confirmed by rigorous studies. During the SPECTRIMS clinical trial of interferon beta1a (Rebif) in secondary progressive MS, depression ratings were obtained from 365 subjects treated either with interferon beta1a or with placebo. No significant differences between groups emerged during 36 months of follow-up. These data suggest that depression is not a side effect of interferon beta1a.

PubMed Disclaimer

Comment in

Publication types

MeSH terms

LinkOut - more resources