[Identification by means of heat denaturation of chromosome aberrations in 6 human metastatic tumors]
- PMID: 1222218
[Identification by means of heat denaturation of chromosome aberrations in 6 human metastatic tumors]
Abstract
The method of chromosome reverse banding was applied to cancer cells. 95 mitotic figures, obtained from 6 histologically different metastatic effusions, in man were studied. This method gives a precise identification of numerical and structural abnormalities in chromosomes. Every possible type of chromosome mutation was observed. The chromosome accidents are different according to their frequence and their stability. This seems to be linked with the genetic contents.