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. 2002 Sep 18;124(37):10972-3.
doi: 10.1021/ja025804o.

A photochemical route for efficient cyclopeptide formation with a minimum of protection and activation chemistry

Axel G Griesbeck  1 , Thomas Heinrich, Michael Oelgemöller, Johann Lex, Arne Molis
Affiliations

A photochemical route for efficient cyclopeptide formation with a minimum of protection and activation chemistry

Axel G Griesbeck et al. J Am Chem Soc. .

Abstract

An elaborated protocol is described which allows the efficient transformation of di-, tri-, and tetrapeptides into cyclopeptides with a minimum of protection and activation chemistry using the photoinduced electron transfer initiated decarboxylation of N-phthaloyl peptides resulting in C-C coupling between the initially formed carbon radicals.

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