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Comparative Study
. 2002 Oct;86(10):1122-6.
doi: 10.1136/bjo.86.10.1122.

Incidence of ROP in two consecutive Swedish population based studies

E Larsson  1 , B Carle-Petrelius, G Cernerud, L Ots, A Wallin, G Holmström
Affiliations
Comparative Study

Incidence of ROP in two consecutive Swedish population based studies

E Larsson et al. Br J Ophthalmol. 2002 Oct.

Abstract

Aims: To prospectively analyse the present incidence of ROP (retinopathy of prematurity) in a well defined geographical area in Sweden, and to compare it with that from a decade earlier in exactly the same area.

Methods: Infants born between 1 August 1998 and 31 July 2000 with a birth weight of 1500 g or less were studied. They were screened for ROP from 5 weeks of postnatal age until the retina was entirely vascularised. The incidence of ROP, with its various stages, was compared with that of a previous (1988-90) population based study in the same geographical area.

Results: The incidence of ROP in the present study was 36.4% (mild (18.2%) and severe ROP (18.2%)), which was similar to that of the previous study. Gestational age at birth remained the most important risk factor for ROP. We found a change in the distribution of ROP. The probability of ROP, particularly severe ROP, was highest in the most immature infants while it was lower in the least immature ones.

Conclusions: The incidence of ROP remained the same in two consecutive population based studies. The more "mature" infants developed ROP, particularly severe ROP, less often, while the most immature infants had ROP more often, particularly severe ROP.

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Figures

Figure 1
Figure 1
(A) Distribution of gestational age at birth (weeks) in the two consecutive groups. (B) Distribution of birth weight (g) in the two consecutive groups.
Figure 2
Figure 2
(A) Mean gestational age at birth (weeks) and standard deviation, in relation to stage of ROP in the two consecutive groups. (B) Mean birth weight (g) and standard deviation, in relation to stage of ROP in the two consecutive groups.
Figure 3
Figure 3
Predicted probability of ROP in relation to gestational age at birth and 95% confidence interval in the two consecutive groups (1990 and 2000) of ≤ 1500 g.
Figure 4
Figure 4
(A) Predicted probability of no, mild, and severe ROP in relation to gestational age at birth in the 1990 group (≤ 1500 g). (B) Predicted probability of no, mild, and severe ROP in relation to gestational age at birth in the 2000 group (≤ 1500 g).
See this image and copyright information in PMC

Comment in

  • Retinopathy of prematurity.
    Donahue SP. Donahue SP. Br J Ophthalmol. 2002 Oct;86(10):1071. doi: 10.1136/bjo.86.10.1071. Br J Ophthalmol. 2002. PMID: 12234878 Free PMC article. No abstract available.

References

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