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Comment
. 2002 Sep 16;196(6):713-8.
doi: 10.1084/jem.20021346.

The formation of lymphatic vessels and its importance in the setting of malignancy

Michael Detmar  1 , Satoshi Hirakawa
Affiliations
Comment

The formation of lymphatic vessels and its importance in the setting of malignancy

Michael Detmar et al. J Exp Med. .
No abstract available

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Figures

Figure 1.
Figure 1.
Hypothetical model of the distinct steps involved in the embryonic development of the mammalian lymphatic vasculature.
Figure 2.
Figure 2.
(A) Traditional model of tumor metastasis via lymphatic and blood vessels. (B) Active lymphangiogenesis model of tumor metastasis.
Figure 2.
Figure 2.
(A) Traditional model of tumor metastasis via lymphatic and blood vessels. (B) Active lymphangiogenesis model of tumor metastasis.
See this image and copyright information in PMC

Comment on

References

    1. Witte, M.H., M.J. Bernas, C.P. Martin, and C.L. Witte. 2001. Lymphangiogenesis and lymphangiodysplasia: from molecular to clinical lymphology. Microsc. Res. Tech. 55:122–145. - PubMed
    1. Asellius, G. 1627. De lactibus sive lacteis venis. Mediolani, Milan.
    1. Gale, N.W., and G.D. Yancopoulos. 1999. Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development. Genes Dev. 13:1055–1066. - PubMed
    1. Carmeliet, P. 2000. Mechanisms of angiogenesis and arteriogenesis. Nat. Med. 6:389–395. - PubMed
    1. Sabin, F.R. 1902. On the origin of the lymphatic system from the veins and the development of the lymph hearts and thoracic duct in the pig. Am. J. Anat. 1:367–391.

MeSH terms