Fuzzy pharmacology: theory and applications
- PMID: 12237153
- DOI: 10.1016/s0165-6147(02)02055-2
Fuzzy pharmacology: theory and applications
Abstract
Fuzzy pharmacology is a term coined to represent the application of fuzzy logic and fuzzy set theory to pharmacological problems. Fuzzy logic is the science of reasoning, thinking and inference that recognizes and uses the real world phenomenon that everything is a matter of degree. It is an extension of binary logic that is able to deal with complex systems because it does not require crisp definitions and distinctions for the system components. In pharmacology, fuzzy modeling has been used for the mechanical control of drug delivery in surgical settings, and work has begun evaluating its use in other pharmacokinetic and pharmacodynamic applications. Fuzzy pharmacology is an emerging field that, based on these initial explorations, warrants further investigation.
Similar articles
-
Neuro-Fuzzy Networks and Their Applications in Medical Fields.Adv Exp Med Biol. 2020;1194:437. doi: 10.1007/978-3-030-32622-7_41. Adv Exp Med Biol. 2020. PMID: 32468559
-
Simulating pharmacokinetic and pharmacodynamic fuzzy-parameterized models: a comparison of numerical methods.J Pharmacokinet Pharmacodyn. 2007 Oct;34(5):595-621. doi: 10.1007/s10928-007-9061-5. Epub 2007 Aug 21. J Pharmacokinet Pharmacodyn. 2007. PMID: 17710517
-
The Work Ratio--modeling the likelihood of return to work for workers with musculoskeletal disorders: A fuzzy logic approach.Work. 2010;36(1):77-87. doi: 10.3233/WOR-2010-1009. Work. 2010. PMID: 20555178
-
Epidemics Fuzzy Decision-Making Applications and Fuzzy Genetic Algorithms Efficiency Enhancement.Adv Exp Med Biol. 2020;1194:73-80. doi: 10.1007/978-3-030-32622-7_7. Adv Exp Med Biol. 2020. PMID: 32468525 Review.
-
Fuzzy logic systems and medical applications.AIMS Neurosci. 2019 Oct 22;6(4):266-272. doi: 10.3934/Neuroscience.2019.4.266. eCollection 2019. AIMS Neurosci. 2019. PMID: 32341982 Free PMC article. Review.
Cited by
-
Spline functions in convolutional modeling of verapamil bioavailability and bioequivalence. I: conceptual and numerical issues.Eur J Drug Metab Pharmacokinet. 2006 Apr-Jun;31(2):79-85. doi: 10.1007/BF03191123. Eur J Drug Metab Pharmacokinet. 2006. PMID: 16898075
-
Genetic fuzzy system predicting contractile reactivity patterns of small arteries.CPT Pharmacometrics Syst Pharmacol. 2014 Apr 2;3(4):e108. doi: 10.1038/psp.2014.3. CPT Pharmacometrics Syst Pharmacol. 2014. PMID: 24695357 Free PMC article.
-
Physiologically based pharmacokinetic modeling of drug disposition in rat and human: a fuzzy arithmetic approach.Pharm Res. 2008 Aug;25(8):1771-81. doi: 10.1007/s11095-007-9447-5. Epub 2008 Mar 25. Pharm Res. 2008. PMID: 18363078
-
Computational systems biology in cancer: modeling methods and applications.Gene Regul Syst Bio. 2007 Sep 17;1:91-110. Gene Regul Syst Bio. 2007. PMID: 19936081 Free PMC article.
-
Adaptive fuzzy modeling of the hypnotic process in anesthesia.J Clin Monit Comput. 2017 Apr;31(2):319-330. doi: 10.1007/s10877-016-9868-y. Epub 2016 Apr 12. J Clin Monit Comput. 2017. PMID: 27072987
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources