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. 1975 Nov-Dec;3(6):1003-9.
doi: 10.1016/0091-3057(75)90008-8.

Effect of aluminum upon conditioned avoidance response acquisition in the absence of neurofibrillary degeneration

G A King, U De Boni, D R Crapper

Effect of aluminum upon conditioned avoidance response acquisition in the absence of neurofibrillary degeneration

G A King et al. Pharmacol Biochem Behav. 1975 Nov-Dec.

Abstract

Aluminum induces neurofibrillary degeneration in cats but not rats. Cats develop a progressive encephalopathy in which an early manifestation is impaired learning-memory performance. At brain aluminum concentrations of 5 to 6 times that found in cat, rats demonstrate an initial transient weight loss and acquisition deficit immediately following intracranial injection. However, rats do not develop a progressive encephalopathy or a chronic learning deficit.

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