[Diagnostic and prognostic value of the separated renin in hypertension due to monolateral nephropathy]

Abstract

Renin activity in renal vein plasma and in peripheral plasma was measured in twentytwo hypertensive patients presenting unilateral renal artery stenosis or other unilateral renal abnormalities. A discrepancy between peripheral and renal vein renin levels was noted only in one case. In seven patients the difference between the renal vein renin of the diseased kidney and that of its contralateral mate was very significant. They responded successfully to surgery for hypertension, confirming the predictive value of a renal vein renin ratio greater than 1.5. In all the other patients with less significant differences between the renin levels of the two kidneys surgery was not performed because they benefited from the hypotensive therapy.