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Review
. 2002 Sep 3;167(5):499-503.

Microalbuminuria in diabetes mellitus

Affiliations
Review

Microalbuminuria in diabetes mellitus

Sheldon W Tobe et al. CMAJ. .
No abstract available

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Figures

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Fig. 1: Guidelines for screening microalbuminuria in patients with diabetes mellitus. BP = blood pressure, ACE = angiotensin-converting-enzyme, CDA = Canadian Diabetes Association.
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Fig. 2: Prevention of progression of renal disease in people with diabetes mellitus. ARB = angiotensin II receptor blocker, ESRD = end-stage renal disease.
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Fig. 3: Possible algorithm for controlling blood pressure in diabetic patients with microalbuminuria. [This algorithm is based on the opinions and practice of the authors.] CCB = long-acting calcium-channel blocker. *On the basis of results of recent clinical trials, start with an ARB or ACE inhibitor. †Possible agents to add are a long-acting dihydropyridine CCB, and a β-blocker if necessary; another possibility instead of these agents is a nondihydropyridine CCB, with no β-blocker, particularly if the patient's heart rate is greater than 80 beats/min.

Comment in

  • Children are not small adults.
    Dean H, Sellers E, Birk P, Blydt-Hansen T, Ogborn M. Dean H, et al. CMAJ. 2003 Feb 4;168(3):255-6; author reply 256. CMAJ. 2003. PMID: 12566324 Free PMC article. No abstract available.

References

    1. Meltzer S, Leiter L, Daneman D, Gerstein HC, Lau D, Ludwig S, et al. 1998 clinical practice guidelines for the management of diabetes in Canada. CMAJ 1998;159(8 Suppl):S1-S29. Available: www.cmaj.ca/cgi/content/full/159/8/DC1. - PMC - PubMed
    1. Tan MH, MacLean DR. Epidemiology of diabetes mellitus in Canada. Clin Invest Med 1995;18:240-6. - PubMed
    1. Young TK, Reading J, Elias B, O'Neil JD. Type 2 diabetes mellitus in Canada's First Nations: status of an epidemic in progress [review]. CMAJ 2000;163:561-6. - PMC - PubMed
    1. 2000 CORR report — dialysis and renal transplantation, Volume I. Ottawa: Canadian Institute for Health Information; 2001.
    1. Krolewski AS, Laffel LM, Krolewski M, Quinn M, Warram JH. Glycosylated hemoglobin and the risk of microalbuminuria in patients with insulin-dependent diabetes mellitus. N Engl J Med 1995;332:1251-5. - PubMed

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