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. 2002 Oct;82(2-3):127-30.
doi: 10.1016/s0378-8741(02)00181-2.

Anti-inflammatory activity and lipid peroxidation inhibition of iridoid lamiide isolated from Bouchea fluminensis (Vell.) Mold. (Verbenaceae)

Rosemeres Horwat Delaporte  1 , Gregorio Martínez Sánchez, Armando Cuellar Cuellar, Attilia Giuliani, João Carlos Palazzo de Mello
Affiliations

Anti-inflammatory activity and lipid peroxidation inhibition of iridoid lamiide isolated from Bouchea fluminensis (Vell.) Mold. (Verbenaceae)

Rosemeres Horwat Delaporte et al. J Ethnopharmacol. 2002 Oct.

Abstract

Anti-inflammatory activity of an ethanolic extract from Bouchea fluminensis leaves was demonstrated. From de ethanolic extract, the active compound was isolated and characterized as the iridoid lamiide. The activity of lamiide on rat-brain phospholipid peroxidation showed a powerful effect (IC(50)=0.92+/-0.01 mM) and an anti-inflammatory activity in carrageenin-induced paw edema test (ED(50)=62.3+/-7 mg/kg weight).

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