Thyrotropin-releasing hormone and amphetamine: a comparison of pharmacological profiles in animals
- PMID: 122589
- DOI: 10.1016/0364-7722(79)90042-0
Thyrotropin-releasing hormone and amphetamine: a comparison of pharmacological profiles in animals
Abstract
1. The pharmacological effects of TRH are compared to those produced by d-amphetamine in an attempt to elucidate the mechanisms underlying the activity of this endogenous peptide. 2. Although numerous amphetamine-like actions have been attributed to TRH, several differences have been noted between these compounds and are discussed. 3. At present, it is impossible to propose a single mechanism of action to explain the behavioral effects of TRH.