Abstract

PIP: The concentrations of prostaglandins present in 23 types of human tissues was estimated. Tissues were obtained from necropsy examinations of adult patients carried out within 24 hours. All tissues were macroscopically free of disease, and in most instances were examined histologically to confirm this. The preparation used was shown to be sensitive to about 0.5 ng/ml. prostaglandins E1, E2, and F2alpha and 2 ng/ml. F1alpha. The recovery of known amounts of added prostaglandins of the different types which were subjected to the standard extraction and separation procedures and then assayed was found to be between 46 and 59 percent.