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. 1975 Dec;152(3):717-20.
doi: 10.1042/bj1520717.

Colchicine inhibition of the heparin-stimulated release of clearing-factor lipase from isolated fat-cells

A Cryer, A McDonald, E R Williams, D S Robinson

Colchicine inhibition of the heparin-stimulated release of clearing-factor lipase from isolated fat-cells

A Cryer et al. Biochem J. 1975 Dec.

Abstract

When isolated fat-cells are incubated at 25 degrees C in serum-based media containing glucose, insulin and heparin, the rise that occurs in the clearing-factor lipase activity of the incubation medium is inhibited by colchicine. The rise in the fat-cell clearing-factor lipase activity that occurs during similar incubations in the absence of heparin is not affected by colchicine.

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References

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