[Comparative efficacy of oxytocin and prostaglandin F2 alpha in the treatment of dyskinesia in primiparas at term]

Abstract

Fifty primiparous women who were in the 25 per cent of patients with the least favourable rate of dilatation of the cervix were treated with drug perfusion therapy for exactly three hours and were assessed graphically three times, each time after 60 minutes. 25 patients, randomly distributed, received between 5-10 and 15 mulli-units of oxytocin per minute and the other 25, 12.5-25 and 37.5 microgrammes ofprostaglandin F2 alpha per minute. The statistical analysis of the results that we obtained has established that: I. both drugs generally behaved with the degree of efficiency one would expect from the doses given; 2. when the cervix is resistant to one of the two products it is generally sensitive to the other; 3. that dystocias do exist refractiory to both drugs, but they are rare.