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doi: 10.1007/BF00431052.
Cerebrospinal fluid levels of chlorpromazine and it metabolites in schizophrenia
- PMID: 1230131
- DOI: 10.1007/BF00431052
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Case Reports
Cerebrospinal fluid levels of chlorpromazine and it metabolites in schizophrenia
Arch Psychiatr Nervenkr (1970).
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Abstract
The concentrations of chlorpromazine and some of its metabolites in blood plasma and CSF from chlorpromazine-treated schizophrenics with different therapeutic results were studied. Compared to a good responder a poor responder showed very high levels of the inactive metabolite chlorpromazine sulphoxide in the CSF.
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