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Review
. 2002 Aug;13(4):329-32.
doi: 10.1016/s0958-1669(02)00330-0.

Production of recombinant proteins in fermenter cultures of the yeast Pichia pastoris

Geoff P Lin Cereghino  1 , Joan Lin Cereghino, Christine Ilgen, James M Cregg
Affiliations
Review

Production of recombinant proteins in fermenter cultures of the yeast Pichia pastoris

Geoff P Lin Cereghino et al. Curr Opin Biotechnol. 2002 Aug.

Abstract

The Pichia pastoris expression system offers economy, ease of manipulation, the ability to perform complex post-translational modifications, and high expression levels. Using this system, recent advances have been made in the quality of recombinant proteins in fermenter culture and in the quality of the protein product, namely improved secretion signals and glycosylation patterns.

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