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. 1975 Sep;32(3):345-51.
doi: 10.1038/bjc.1975.233.

Levamisole treatment of local and metastatic growth of transplanted rat tumours

D G Hopper, M V Pimm, R W Baldwin
Free PMC article

Levamisole treatment of local and metastatic growth of transplanted rat tumours

D G Hopper et al. Br J Cancer. 1975 Sep.
Free PMC article

Abstract

Levamisole has been examined for its ability to control local growth and pulmonary metastases of transplanted rat tumours. The compound did not suppress subcutaneous growth of 3-methylcholanthrene induced sarcomata when administered systemically in a variety of regimens, or when injected in admixture with tumour cells. In addition, levamisole treatment failed to suppress pulmonary growth of intravenously transferred sarcoma cells or spontaneous pulmonary metastases appearing after surgical removal of a transplanted epithelioma.

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