Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1975;10(5-6):285-8.
doi: 10.1016/s0014-4908(75)80035-4.

Manganese induced hepatic lesions in carbon tetrachloride pretreated rats

S V Chandra, D K Saxena

Manganese induced hepatic lesions in carbon tetrachloride pretreated rats

S V Chandra et al. Exp Pathol (Jena). 1975.

Abstract

Manganese sulphate (6 mg/kg) was administered intraperitoneally daily for 30 days in carbon tetrachloride pretreated rats. Histological and histochemical studies in liver tissue revealed extensive damage to hepatic parenchyma in these rats as compared to lesions produced by manganese sulphate alone. These findings suggest that workers, with liver dysfunction ergated in manganese industry may be more susceptible to the toxic effects of this metal.

PubMed Disclaimer