Comparative Study
Treatment of diabetes insipidus with 1-deamino-8-d-arginine vasopressin
- PMID: 1233863
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Comparative Study
Treatment of diabetes insipidus with 1-deamino-8-d-arginine vasopressin
Acta Med Acad Sci Hung.
1975.
Abstract
The effect on water metabolism of 1-deamino-8-D-arginine vasopressin and lysine vasopressin have been studied and compared in 20 vasopressin-sensitive and 2 ADH-resistant diabetes insipidus patients. In every case of ADH-sensitive diabetes insipidus, diuresis decreased and the urinary osmolality increased more markedly and for a longer time with the former than with the latter drug. Both drugs were ineffective in patients with ADH-resistant diabetes insipidus. Administration of 1-deamino-8-D-arginine vasopressin did not cause any side effect. It is concluded that 1-deamino-8-D-arginine vasopressin can successfully be employed in the treatment of ADH-sensitive diabetes insipidus.
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