Changes in drug metabolism with increasing age: 1. warfarin binding and plasma proteins
- PMID: 1234489
- PMCID: PMC1402487
- DOI: 10.1111/j.1365-2125.1975.tb00474.x
Changes in drug metabolism with increasing age: 1. warfarin binding and plasma proteins
Abstract
1 A decrease was found in the binding capacity of elderly people for warfarin. 2 The decrease in binding correlated with a fall in plasma albumin concentrations. 3 No changes in the association constant were observed.
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