Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1975 Feb;2(1):69-72.
doi: 10.1111/j.1365-2125.1975.tb00474.x.

Changes in drug metabolism with increasing age: 1. warfarin binding and plasma proteins

M J Hayes, M J Langman, A H Short
Comparative Study

Changes in drug metabolism with increasing age: 1. warfarin binding and plasma proteins

M J Hayes et al. Br J Clin Pharmacol. 1975 Feb.

Abstract

1 A decrease was found in the binding capacity of elderly people for warfarin. 2 The decrease in binding correlated with a fall in plasma albumin concentrations. 3 No changes in the association constant were observed.

PubMed Disclaimer

References

    1. J Clin Invest. 1969 Jan;48(1):193-202 - PubMed
    1. Gerontologia. 1966;12(1):30-6 - PubMed
    1. J Biol Chem. 1951 Nov;193(1):265-75 - PubMed
    1. Acta Med Scand Suppl. 1958;339:1-62 - PubMed
    1. Geriatrics. 1955 May;10(5):232-8 - PubMed

Publication types

LinkOut - more resources