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. 2002 Oct;44(1):52-8.
doi: 10.1016/s0720-048x(01)00468-5.

Differentiation of prostate cancer from benign prostate hypertrophy using dual-echo dynamic contrast MR imaging

Satoshi Muramoto  1 , Hidemasa Uematsu, Hirohiko Kimura, Yoshiyuki Ishimori, Norihiro Sadato, Nobuyuki Oyama, Tsuyoshi Matsuda, Yasutaka Kawamura, Yoshiharu Yonekura, Kenichiro Okada, Harumi Itoh
Affiliations

Differentiation of prostate cancer from benign prostate hypertrophy using dual-echo dynamic contrast MR imaging

Satoshi Muramoto et al. Eur J Radiol. 2002 Oct.

Abstract

Objective: To investigate the usefulness of dynamic contrast magnetic resonance (MR) imaging in the differentiation of prostate cancer (PC) from benign prostate hypertrophy (BPH).

Materials and methods: Eleven PC patients and 13 BPH patients were entered into the analysis. The mean gradient (MG) was calculated from the T2* term-eliminated time-signal intensity curve obtained from dynamic contrast MR data, and the MG of PC and that of BPH were compared.

Results: The MG of PC was significantly higher than that of BPH. When the threshold value was set to 1.88% per s for discriminating PC from BPH, the sensitivity, specificity, and accuracy were 100, 85, and 92%, respectively.

Conclusion: The MG, which is derived from the T2* term-eliminated time-signal intensity curve, may be a useful index for differentiating PC from BPH.

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