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Review
. 2002 Oct;5(5):499-505.
doi: 10.1016/s1369-5274(02)00356-9.

Functional and evolutionary analysis of a eukaryotic parasitic genome

Christian P Vivarès  1 , Manolo Gouy, Fabienne Thomarat, Guy Méténier
Affiliations
Review

Functional and evolutionary analysis of a eukaryotic parasitic genome

Christian P Vivarès et al. Curr Opin Microbiol. 2002 Oct.

Abstract

The DNA sequences of the 11 linear chromosomes of the approximately 2.9 Mbp genome of Encephalitozoon cuniculi, an obligate intracellular parasite of mammals, include approximately 2000 putative protein-coding genes. The compactness of this genome is associated with the length reduction of various genes. Essential functions are dependent on a minimal set of genes. Phylogenetic analysis supports the hypotheses that microsporidia are related to fungi and have retained a mitochondrion-derived organelle, the mitosome.

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