Breast cancer banishes p27 from nucleus
- PMID: 12357238
- DOI: 10.1038/nm1002-1076
Breast cancer banishes p27 from nucleus
Comment on
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PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization.Nat Med. 2002 Oct;8(10):1145-52. doi: 10.1038/nm759. Epub 2002 Sep 16. Nat Med. 2002. PMID: 12244301
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PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest.Nat Med. 2002 Oct;8(10):1153-60. doi: 10.1038/nm761. Epub 2002 Sep 16. Nat Med. 2002. PMID: 12244302
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Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer.Nat Med. 2002 Oct;8(10):1136-44. doi: 10.1038/nm762. Epub 2002 Sep 16. Nat Med. 2002. PMID: 12244303
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PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest.Nat Med. 2002 Oct;8(10):1153-60. doi: 10.1038/nm761. Epub 2002 Sep 16. Nat Med. 2002. PMID: 12244302
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