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. 1975 Sep:4 Pt 2:429-33.

The immunology of asbestosis

E Kagan, I Webster, J C Cochrane, K Miller
  • PMID: 1236232

The immunology of asbestosis

E Kagan et al. Inhaled Part. 1975 Sep.

Abstract

Forty-one employees with varying degrees of asbestosis have been tested for any alteration in the immunological profile. Of these, twenty-two employees showed evidence of pleural thickening and nineteen parenchymal asbestotic fibrosis. Those employees showing pleural thickening gave a strong reaction to different skin tests and a few of those with a parenchymal asbestotic fibrosis showed depressed cutaneous reactivity. Lymphocytotoxic antibodies were present in the sera of 60% of those with pleural thickening and 94% of those with parenchymal asbestosis. An immunological screening schedule is suggested for those employees who show pleural thickening.

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