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Review
. 2002 Oct;27(10):495-7.
doi: 10.1016/s0968-0004(02)02189-8.

YTH: a new domain in nuclear proteins

Peter Stoilov  1 , Ilona Rafalska, Stefan Stamm
Affiliations
Review

YTH: a new domain in nuclear proteins

Peter Stoilov et al. Trends Biochem Sci. 2002 Oct.

Abstract

A novel 100-150-residue domain has been identified in the human splicing factor YT521-B and its Drosophila and yeast homologues. Homology searches show that the domain is typical for the eukaryotes and is particularly abundant in plants. It is predicted to adopt a mixed alpha-helix-beta-sheet fold and to bind to RNA. We propose the name YTH (for YT521-B homology) for the domain.

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