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. 2002 Apr;2(2):185-200.
doi: 10.2174/1389557024605492.

Daphnane-type diterpene orthoesters and their biological activities

Weidong He  1 , Miroslav Cik, Giovanni Appendino, Luc Van Puyvelde, Josée E Leysen, Norbert De Kimpe
Affiliations

Daphnane-type diterpene orthoesters and their biological activities

Weidong He et al. Mini Rev Med Chem. 2002 Apr.

Abstract

Daphnane orthoesters are the active ingredients of plant remedies from the Western, Chinese and African traditional medicine, and have provided important tools to investigate medicinally relevant processes like tumour promotion, apoptosis, neurotrophism, and VR1 activation. The occurrence, biological activity, and molecular pharmacology of these compounds will be reviewed.

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