Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1975 Jun 13;12(1):13-22.
doi: 10.1007/BF02339805.

The action of ionizing radiation on DNA in the presence of quinacrine. II. DNA strand breakage

A Hissung, H Dertinger

The action of ionizing radiation on DNA in the presence of quinacrine. II. DNA strand breakage

A Hissung et al. Radiat Environ Biophys. .

Abstract

Strand breakage of DNA irradiated in solution and in the dry state in the presence of quinacrine was investigated by sedimentation analysis. Determination of single strand breaks in solution combined with binding studies permits to conclude that bound quinacrine protects DNA more effectively than the free compound. In the dry state quinacrine is without detectable effect on both single and double strand break formation, neither under aerobic nor anaerobic conditions.

PubMed Disclaimer

References

    1. Radiat Environ Biophys. 1975 Jun 13;12(1):5-12 - PubMed
    1. Nature. 1974 May 17;249(454):248-50 - PubMed
    1. Biopolymers. 1968;6(9):1225-53 - PubMed
    1. J Mol Biol. 1964 Jan;8:1-10 - PubMed
    1. Strahlentherapie. 1965 Dec;128(4):565-76 - PubMed