Case Reports
Successful treatment of familial Mediterranean fever attacks with thalidomide in a colchicine resistant patient
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- PMID: 12371635
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Case Reports
Successful treatment of familial Mediterranean fever attacks with thalidomide in a colchicine resistant patient
Clin Exp Rheumatol.
2002 Jul-Aug.
Abstract
Colchicine is the treatment of choice in familial Mediterranean fever (FMF) both for attacks and for prevention of secondary amyloidosis. The overall non-responder rate varies from 5-10 to 40%. Thalidomide is known to blunt the acute phase response. We report the efficacy of the addition of thalidomide to colchicine in controlling the febrile attacks and acute phase response in a patient with FMF resistant to 2 mg colchicine per day.
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