doi: 10.1016/s0306-9877(02)00220-7.
BCR-ABL insufficiency for the transformation of human stem cells into CML
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- PMID: 12376083
- DOI: 10.1016/s0306-9877(02)00220-7
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BCR-ABL insufficiency for the transformation of human stem cells into CML
Med Hypotheses.
2002 Nov.
Abstract
On the basis of numerical and kinetic data, the paper argues against the tenet that BCR-Abl is sufficient for transforming into Chronic Myelogenous leukemia a human hemopoietic stem cell, regardless of degree of pluripotency.
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