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. 2002 Nov;59(5):588-9.
doi: 10.1016/s0306-9877(02)00220-7.

BCR-ABL insufficiency for the transformation of human stem cells into CML

G T Matioli  1
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BCR-ABL insufficiency for the transformation of human stem cells into CML

G T Matioli. Med Hypotheses. 2002 Nov.

Abstract

On the basis of numerical and kinetic data, the paper argues against the tenet that BCR-Abl is sufficient for transforming into Chronic Myelogenous leukemia a human hemopoietic stem cell, regardless of degree of pluripotency.

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