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Review
. 2002 Nov;61 Suppl 2(Suppl 2):ii74-7.
doi: 10.1136/ard.61.suppl_2.ii74.

Effects of anakinra on clinical and radiological outcomes in rheumatoid arthritis

B Bresnihan  1
Affiliations
Review

Effects of anakinra on clinical and radiological outcomes in rheumatoid arthritis

B Bresnihan. Ann Rheum Dis. 2002 Nov.
No abstract available

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Figures

Figure 1
Figure 1
American College of Rheumatology 20% response (ACR20) after treatment with anakinra administered as monotherapy, compared with placebo, in patients with rheumatoid arthritis. The early onset of action is demonstrated.
Figure 2
Figure 2
Magnitude of the American College of Rheumatology clinical responses after treatment with anakinra administered in combination with methotrexate in patients with rheumatoid arthritis (*p<0.05 v placebo).
Figure 3
Figure 3
Improvements in individual American College of Rheumatology criteria components after treatment with anakinra administered in combination with methotrexate. Patient centred outcomes are included in panel A; physician centred outcomes are included in panel B (*p<0.05; **p<0.01; ***p<0.001 v placebo).
Figure 4
Figure 4
Improvements in the Health Assessment Questionnaire (HAQ) disease index from the three efficacy studies of anakinra. Clinically relevant improvements (>-0.22) were observed in all.
See this image and copyright information in PMC

References

    1. Arthritis Rheum. 2000 May;43(5):1001-9 - PubMed
    1. N Engl J Med. 2000 Sep 7;343(10):732-4 - PubMed
    1. Curr Opin Rheumatol. 2001 May;13(3):170-6 - PubMed
    1. Arthritis Rheum. 1998 Dec;41(12):2196-204 - PubMed
    1. Arthritis Rheum. 1980 Feb;23(2):137-45 - PubMed

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