doi: 10.1111/j.1399-0004.1975.tb00333.x.
Familial balanced (7;11;21) translocation and Down's syndrome in two siblings
- PMID: 123836
- DOI: 10.1111/j.1399-0004.1975.tb00333.x
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Familial balanced (7;11;21) translocation and Down's syndrome in two siblings
Clin Genet.
1975 Apr.
Abstract
Cytogenetic studies of a family with two children with Down's syndrome have revealed a balanced reciprocal translocation between chromosomes No. 7, 11 and 21 in the mother. One of three daughters has inherited this translocation. two mongoloid daughters have a supernumerary chromosome No. 21 in addition to the translocation.
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