Perception of the risk of adverse drug reactions: differences between health professionals and non health professionals
- PMID: 12392593
- PMCID: PMC1874441
- DOI: 10.1046/j.1365-2125.2002.01674.x
Perception of the risk of adverse drug reactions: differences between health professionals and non health professionals
Abstract
Aims: To investigate how risk of adverse drug reactions (ADRs) of several drug classes is perceived by health vs non health professionals.
Methods: Four hundred health professionals (i.e. 278 general practitioners, 76 pharmacists and 46 pharmacovigilance professionals) and 153 non health professionals were interviewed. Visual analogue scales were used to define a score of perceived risk of ADRs associated with each drug class (ranking from 0 to 10).
Results: Anticoagulants were ranked as the most dangerous drugs by general practitioners [median score (25th-75th centiles): 7.9 (6.7-9.0)], pharmacists [8.7 (7.8-9.7)] and pharmacovigilance professionals [8.1 (7.2-9.0)]. For non health professionals, the class ranked first was sleeping pills [8.7 (7.2-9.4)] followed by tranquillisers [8.2 (6.4-9.2)] and antidepressants [8.0 (5.9-9.1)]. Aspirin was listed in the last position by non health professionals [3.4 (1.5-5.4)].
Conclusions: There are major differences in the perception of risk of ADRs between health professionals and non health professionals.
Similar articles
-
Perception of the risk of gastrointestinal adverse drug reactions with non-steroidal anti-inflammatory drugs (including coxibs): differences among general practitioners, gastroenterologists and rheumatologists.Eur J Clin Pharmacol. 2003 Nov;59(8-9):685-8. doi: 10.1007/s00228-003-0648-5. Epub 2003 Oct 11. Eur J Clin Pharmacol. 2003. PMID: 14556042
-
Perception of risk of adverse drug reactions: a 3-year follow-up of a cohort of medical students.Fundam Clin Pharmacol. 2010 Aug;24(4):423-7. doi: 10.1111/j.1472-8206.2009.00783.x. Epub 2009 Oct 21. Fundam Clin Pharmacol. 2010. PMID: 19845768
-
Perception of risk of adverse drug reactions by medical students: influence of a 1 year pharmacological course.Br J Clin Pharmacol. 2007 Aug;64(2):233-6. doi: 10.1111/j.1365-2125.2007.02882.x. Epub 2007 Mar 22. Br J Clin Pharmacol. 2007. PMID: 17381466 Free PMC article.
-
Reporting of adverse drug reactions in India: A review of the current scenario, obstacles and possible solutions.Int J Risk Saf Med. 2019;30(1):33-44. doi: 10.3233/JRS-180025. Int J Risk Saf Med. 2019. PMID: 30175985 Review.
-
Evaluation of patient reporting of adverse drug reactions to the UK 'Yellow Card Scheme': literature review, descriptive and qualitative analyses, and questionnaire surveys.Health Technol Assess. 2011 May;15(20):1-234, iii-iv. doi: 10.3310/hta15200. Health Technol Assess. 2011. PMID: 21545758 Review.
Cited by
-
Active pharmacovigilance in China: recent development and future perspectives.Eur J Clin Pharmacol. 2018 Jul;74(7):863-871. doi: 10.1007/s00228-018-2455-z. Epub 2018 Apr 10. Eur J Clin Pharmacol. 2018. PMID: 29637279 Review.
-
Serious adverse events reported for antiobesity medicines: postmarketing experiences from the EU adverse event reporting system EudraVigilance.Int J Obes (Lond). 2016 Nov;40(11):1742-1747. doi: 10.1038/ijo.2016.135. Epub 2016 Aug 1. Int J Obes (Lond). 2016. PMID: 27478924
-
Perception of the risk of gastrointestinal adverse drug reactions with non-steroidal anti-inflammatory drugs (including coxibs): differences among general practitioners, gastroenterologists and rheumatologists.Eur J Clin Pharmacol. 2003 Nov;59(8-9):685-8. doi: 10.1007/s00228-003-0648-5. Epub 2003 Oct 11. Eur J Clin Pharmacol. 2003. PMID: 14556042
-
Development and validation of prescription drug risk, efficacy, and benefit perception measures in the context of direct-to-consumer prescription drug advertising.Res Social Adm Pharm. 2021 May;17(5):942-955. doi: 10.1016/j.sapharm.2020.07.028. Epub 2020 Aug 6. Res Social Adm Pharm. 2021. PMID: 32883618 Free PMC article.
-
Knowledge and attitudes of HIV-infected patients on antiretroviral therapy regarding adverse drug reactions (ADRs) in selected hospitals in Nigeria.Perspect Clin Res. 2012 Jul;3(3):95-101. doi: 10.4103/2229-3485.100657. Perspect Clin Res. 2012. PMID: 23125960 Free PMC article.
References
-
- Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA. 1998;279:1200–1205. - PubMed
-
- Einarson TR. Drug-related hospital admissions. Ann Pharmacother. 1993;27:832–840. - PubMed
-
- Classen DC, Pestotnik SL, Evans RS, Lloyd JF, Burke JP. Adverse drug events in hospitalized patients. Excess length of stay, extra costs, and attributable mortality. JAMA. 1997;277:301–306. - PubMed
-
- Cosentino M, Leoni O, Oria C, et al. Hospital-based survey of doctors' attitudes to adverse drug reactions and perception of drug-related risk for adverse reaction occurrence. Pharmacoepidemiol Drug Safety. 1999;8:S27–S35. - PubMed
MeSH terms
LinkOut - more resources
Full Text Sources
Medical